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Furthermore, smaller clinical trials as well as pre-clinical studies have provided some, albeit not conclusive, support for the clinical outcomes-based evidence of the benefit of GLP-1 RAs in HF

Since GLP-1 receptors are also located in the brain, these medications may help support neuronal communication and reduce "neuro-inflammation." By helping the brain manage its energy supply better, they may indirectly help clear the metabolic "fog" caused by declining estrogen

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An AM protocol may still be blunted if you drink heavily the night before, as your system would still be recovering